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Activepieces vs BIOS
Open-source automation, focuses on generic tasks rather than drug discovery pipelines.
ActivepiecesOpen-source no-code automation, a Zapier alternative
BIOSAI Scientist for biomedical research - #1 on BixBenchWhich to pick
Pick Activepieces if you want…
- Open-source Zapier alternative
- Open-source no-code automation
- Integrations with Slack, HubSpot or QuickBooks (on Activepieces' list, not BIOS's)
Pick BIOS if you want…
- AI-guided peptide binder design
- Integrations with Linux x64, Linux ARM64 or Apple-silicon macOS (on BIOS's list, not Activepieces')
Side by side
- What it is
- Activepieces:Activepieces is an open-source no-code automation platform with AI agents, flows, tables and 760+ integrations.
- BIOS:BIOS is an AI Scientist that designs, builds, and validates therapeutic peptide binders from a single prompt.
- Best for
- Activepieces:Open-source Zapier alternative
- BIOS:AI-guided peptide binder design
- Who it’s for
- Activepieces:Teams that need visual workflow automation and AI-driven agents without heavy coding.
- BIOS:Biomedical researchers and drug discovery teams seeking AI-driven design and lab automation.
- Pricing
- Activepieces:Freemium
- BIOS:Freemium
- Plans
- Activepieces:Free $0 · Plus $20 per month · Team $200 per month · Embed From $36k a year per year
- BIOS:—
- Open source
- Activepieces:Yes, 24,830 GitHub stars
- BIOS:Yes
- Works with
- Activepieces:Slack, HubSpot, QuickBooks, Stripe, GitHub, HashiCorp Vault
- BIOS:Linux x64, Linux ARM64, Apple-silicon macOS, RFdiffusion3, BoltzGen, PXDesign, Boltz-2, ESMFold2
Activepieces features
- AI-driven agents. Describe a job in plain language and an agent orchestrates steps across connected apps.
- Visual flow builder. Drag-and-drop designer with branching, retries, sub-flows and inline TypeScript.
- Unlimited integrations. 760+ open-source pieces connect to any API, plus custom HTTP piece.
- Team governance. Projects, SSO (Okta/Entra), role-based permissions, audit logs and secret managers.
- Self-host or cloud. Run on Activepieces Cloud, Docker/Kubernetes, or fully air-gapped on-prem.
- Tables & knowledge base. Shared data tables and searchable docs accessible to all flows and agents.
BIOS features
- Literature Agent. Plans research questions, searches papers, patents and databases, and returns a cited answer.
- Binder Generation. Three generative models propose candidates and six orthogonal filters shortlist the most promising designs.
- Autonomous Lab. A synthesis box and robotic arm synthesize top designs and assay them on live cells, feeding results back to the model.
- CLI Workspace. Full command-line interface for running design, analysis, and workflow commands from the terminal.
- Human-in-the-Loop. Allows users to intervene at checkpoints or run fully autonomous pipelines.
- Open Model Stack. Runs open models such as RFdiffusion3, BoltzGen, PXDesign, RFdiffusion3, Boltz-2, ESMFold2, mmseqs2 and Foldseek.
Activepieces vs BIOS FAQ
Is Activepieces or BIOS free?+
Activepieces has a free plan; paid plans start at $20/month (Plus). BIOS has a free plan and paid plans.
Is Activepieces or BIOS open source?+
Yes, both are open source: Activepieces (activepieces/activepieces on GitHub) and BIOS (bio-xyz/BioAgents on GitHub).
Do Activepieces and BIOS integrate with the same tools?+
Their integration lists don't overlap: Activepieces lists Slack, HubSpot, QuickBooks, Stripe and 2 more; BIOS lists Linux x64, Linux ARM64, Apple-silicon macOS, RFdiffusion3 and 6 more.
On DevHunt
Based on each tool's website and DevHunt data. Details may change; check the official sites.